- The most important scientific studies on Cannabidiol (CBD) in 201711 February 2018
In 2017 a lot of research has been done about the cannabinoid CBD and how it works.
The abbreviation CBD stands for cannabidiol. It is a non-psychoactive cannabinoid that can be isolated from hemp or cannabis. CBD is found in both cannabis sativa and indica.
Below is an overview of scientific studies related to Cannabidiol
- Science / Human: According to a case series, CBD can be effective in epilepsy due to a brain tumor
In three patients with refractory attacks and a medical history of a primary brain tumor, two showed an improvement in the frequency of attacks and all three had an improvement in the severity of the attack. They participated in the CBD Program at the University of Alabama in Birmingham (USA).
An epilepsy, which often occurs in patients with a brain tumor, is often refractory to standard therapy. The aim of the study was to investigate the certainty and efficacy of a CBD-rich cannabis extract (Epidiolex, GW Pharmaceuticals). The authors wrote that “these pilot results suggest that CBD should be further investigated for the treatment of brain tumor-associated epilepsy”.
Warren PP, Bebin EM, Nabors LB, Szaflarski JP. The use of cannabidiol for the management of seizures in patients with brain tumor-related epilepsy. Neurocase. October 24, 2017: 1-5. [in the press]
- Science / Cells: Effects of radiation on glioblastoma cells were increased with CBD
CBD (cannabidiol) increased the effects of radiation for killing human glioblastoma cells. Glioblastoma is an aggressive brain tumor.
Columbia University, New York, USA.
Ivanov VN, et al. Oncotarget. 2017 May 27. [In press]
- Science / Cells: THC and CBD can increase anti-cancer activity of standard chemotherapy in leukemia
Studies with leukemia cells suggest that THC and CBD used with anti-leukemia medication (cytarabine and vincristine) may drastically allow the permitted dose of the cytotoxic agents, but still remain safe. “Use of cannabinoid after chemotherapy resulted in greater induction of apoptosis, while this was the opposite when the administration schedule was reversed.” Apoptosis is a form of cell death display.
University of London, UK.
Scott KA, et al. Int J Oncol. 2017 May 29. [In print]
- Science / Human: The anxiolytic effect of CBD was highest after an average dose
The administration of CBD reduces anxiety with a dose-negative curve in healthy subjects. The subjective anxiety measurements were reduced by 300 mg CBD, but not by 100 and 900 mg CBD in a situation that causes anxiety (test for public speaking).
University of São Paulo, Brazil.
Zuardi AW, et al. Front Pharmacol. 2017; 8: 259.
- Science / Human: CBD-rich cannabis reduced seizures in children with epilepsy according to a survey
Cannabis, rich in CBD (Cannabidiol), was used in 43 children from Mexico, 51% to a moderate to marked decrease in seizures and 16% to seizures-free. This was the result of a survey among parents. The number of antiepileptic drugs was reduced in 9 of the 43 (20.9%) cases. No serious side effects are indicated.
Institute Tecnológico de Estudios Superiores de Monterrey, Campus Salud, Mexico.
Aguirre-Velázquez CG. Neurol Res Int. 2017; 2017: 2985729